Independently derived targeting of 28S rDNA by A- and D-clade R2 retrotransposons

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Long-term inheritance of the 28S rDNA-specific retrotransposon R2.

R2 is a non-long-terminal-repeat (LTR) retrotransposon that inserts specifically into 28S rDNA. R2 has been identified in many species of arthropods and three species of chordates. R2 may be even more widely distributed in animals, and its origin may be traceable to early animal evolution. In this study, we identified R2 elements in medaka fish, White Cloud Mountain minnow, Reeves' turtle, hagf...

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Although most non-long terminal repeat (non-LTR) retrotransposons are inserted throughout the host genome, many non-LTR elements in the R1 clade are inserted into specific sites within the target sequence. Four R1 clade families have distinct target specificity: R1 and RT insert into specific sites of 28S rDNA, and TRAS and SART insert into different sites within the (TTAGG)(n) telomeric repeat...

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ژورنال

عنوان ژورنال: Mobile Genetic Elements

سال: 2011

ISSN: 2159-256X

DOI: 10.4161/mge.1.1.16485